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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
11.82
Human Site:
T483
Identified Species:
21.67
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
T483
P
P
A
C
Q
L
S
T
P
Y
G
Q
P
A
C
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
T483
P
P
A
C
Q
L
S
T
P
Y
G
Q
P
A
C
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
W444
P
P
M
S
A
S
K
W
F
D
P
K
S
I
C
Dog
Lupus familis
XP_539016
855
96614
T481
P
S
A
C
Q
L
S
T
P
Y
S
Q
L
A
H
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
P479
N
D
F
P
P
A
C
P
S
S
T
P
Y
S
Q
Rat
Rattus norvegicus
NP_001101642
835
94323
T461
P
P
A
C
P
S
S
T
P
Y
S
Q
L
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
K486
C
F
R
T
P
V
V
K
S
V
F
P
S
G
G
Chicken
Gallus gallus
XP_419867
879
99691
I487
M
E
C
F
R
T
P
I
V
R
N
N
F
S
P
Frog
Xenopus laevis
NP_001082090
882
99060
Y485
V
N
K
S
Q
E
D
Y
M
N
C
F
R
T
P
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
T545
P
A
L
I
T
K
H
T
S
P
E
D
R
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
K458
G
G
S
S
E
V
H
K
V
I
S
S
D
C
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
F443
D
Y
A
T
A
Y
G
F
C
Q
E
I
G
Y
L
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
R430
S
A
S
L
S
N
N
R
N
I
I
T
V
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
73.3
N.A.
0
66.6
N.A.
0
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
73.3
N.A.
6.6
66.6
N.A.
6.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
39
0
16
8
0
0
0
0
0
0
0
31
8
% A
% Cys:
8
0
8
31
0
0
8
0
8
0
8
0
0
8
24
% C
% Asp:
8
8
0
0
0
0
8
0
0
8
0
8
8
0
8
% D
% Glu:
0
8
0
0
8
8
0
0
0
0
16
0
0
0
0
% E
% Phe:
0
8
8
8
0
0
0
8
8
0
8
8
8
0
0
% F
% Gly:
8
8
0
0
0
0
8
0
0
0
16
0
8
8
8
% G
% His:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
8
0
16
8
8
0
8
0
% I
% Lys:
0
0
8
0
0
8
8
16
0
0
0
8
0
8
0
% K
% Leu:
0
0
8
8
0
24
0
0
0
0
0
0
16
0
8
% L
% Met:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
8
8
0
8
8
8
8
0
8
0
% N
% Pro:
47
31
0
8
24
0
8
8
31
8
8
16
16
0
16
% P
% Gln:
0
0
0
0
31
0
0
0
0
8
0
31
0
0
8
% Q
% Arg:
0
0
8
0
8
0
0
8
0
8
0
0
16
0
8
% R
% Ser:
8
8
16
24
8
16
31
0
24
8
24
8
16
16
0
% S
% Thr:
0
0
0
16
8
8
0
39
0
0
8
8
0
8
8
% T
% Val:
8
0
0
0
0
16
8
0
16
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
8
0
31
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _